Restylane & Perlane — a Showdown

Each year, more and more dermal fillers are introduced to the marketplace. It can be confusing knowing which filler works best to address which issue.

Restylane and Perlane are two of those. Both are hyaluronic acid (the naturally occurring substance in the skin that is responsible for giving the skin volume and plumpness) fillers. Both are made by the same company, QMed. Both fillers are injected to fill the space between collagen and elastin fibers within the skin to restore lost volume. Both attract and bind with water molecules to hydrate and fill the injected area.

 Injection TherapiesSo, what’s the difference between the two? It turns out Perlane and Restylane are perfect complements to each other.

Perlane is thicker
Perlane is more highly crosslinked than Restylane. What does that mean? Crosslinking is the process that allows fillers to remain in the tissue. Crosslinking makes a filler thicker, in this case three times thicker than Restylane.

Because it is thicker, Perlane needs the presence of fat to help hide the filler. So, the cheeks, chin, and nasolabial folds are the places where Perlane excels. Perlane is designed to fill moderate to severe facial folds.

Restylane is thinner
Restylane is thinner than Perlane, allowing it to flow when injected. This is perfect for addressing hollowing that occurs underneath the eyes. It also works very well to define the edges of the lips. It is designed for sensitive areas with finer wrinkles and thinner skin.

Restylane also wins the popularity contest. It has been used in over 11 million treatments.

Both of these fillers deliver remarkable results. Call us at Laser & Mohs Dermatology, 212-391-8600, and let’s discuss how we can put Perlane and Restylane to work for your needs.

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