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dermal fillers new york city

Restylane Refyne & Defyne


What Is Restylane®?

Restylane Laser and Mohs NYC

Restylane® was the first dermal filler in the U.S., approved back in 2006. Since then, Restylane®, along with Juvederm®, have been the world’s most popular dermal fillers. Over the years, both product lines have expanded to specifically target areas such as the lips with Restylane® Silk or Juvederm® Volbella®.


Types Of Restylane®

The full Restylane® line now includes five fillers: Restylane®, Restylane® Silk, Restylane® Lyft, Restylane® Refyne™, and Restylane® Defyne™. Here at Laser & Mohs Dermatology of New York, we offer the full family of Restylane® dermal fillers for our Manhattan area patients.


What is Restylane® Refyne?

Restylane Refyne NYC

Restylane® Refyne™ was approved by the FDA in December 2016. This new addition to the Restylane® line (along with Defyne™, see below) is used to correct smile (marionette) lines and nasolabial folds. Refyne™ is specifically formulated to treat mild to moderate lines and wrinkles.

Learn more about Restylane Refyne/Defyne with Dr. Quintana’s Q&A


What Areas Can Restylane® Refyne™ Treat?

Restylane® Refyne™ is used to treat:Restylane Refyne NYC

  • Mild to moderate wrinkles and lines
  • Mild marionette lines and nasolabial folds
  • Fine lines on the cheeks
  • Lips
  • Brow lines
  • Tear trough

What is Restylane® Defyne™?

Restylane Defyne Manhattan NYC

Approved by the FDA along with Refyne™, Defyne™ also specifically targets nasolabial folds and marionette lines. The difference is that Defyne™ is designed for use on moderate to severe creases and lines. Both Refyne™ and Defyne™ provide results that last up to one year.

What Areas Can Restylane® Defyne™ Treat?

Restylane® Defyne™ is used to treat:Restylane Defyne NYC

  • Deep-set folds and wrinkles
  • Moderate to severe marionette lines and nasolabial folds
  • Jawline contoruing
  • Cheek contouring
  • Deep frown lines

Why Choose Restylane® Refyne™ and Restylane® Defyne™?

There are definitely other options for addressing nasolabial folds and marionette lines, but Refyne™ and Defyne™ are different. XpressHAn Technology™ is a cross-linking in the gel of both Restylane® Refyne™ and Defyne™ to help support the patient’s natural expressions — for real-life results that help maintain natural movement when smiling, frowning, or otherwise moving your mouth.

What does this mean? If you’re reading this page, you know about dermal fillers. In some cases, injection into the nasolabial folds and other areas around the mouth can create an unnatural inability of the facial skin to move with certain facial expressions. Galderma says its technology now allows Refyne™ and Defyne™ to fill the creases, all the while letting your skin move naturally when you make expressions.


Restylane® Defyne™ Before And After

Restylane NYC

Patient Testimonial

“I had such a wonderful experience at Laser & Mohs!! Dr. Quintana makes you feel so comfortable and really explains each treatment in detail. She is always honest and gives her best advice when choosing a treatment. I have also seen her results for Restylane® – extremely natural!! I would highly recommend Dr. Quintana and Laser & Mohs to anyone in the NYC area”


What’s The Difference Between Restylane® Refyne™ and Defyne™?

The main difference between Restylane® Refyne™ and Defyne™ is the severity of the wrinkles and lines they treat. Restylane® Refyne™ treats mild to moderate wrinkles and lines. Restylane® Defyne™ treats moderate to severe lines.


How Many Treatments Of Restylane® Will I Need?

Restylane® Refyne™ and Restylane® Defyne™ are single session dermal fillers. One session takes just 15-20 minutes. Your results are immediate as these fillers instantly fill smile and marionette lines.

Results Of Restylane® Refyne™ and Defyne™

Both of these fillers provide results that last up to one year. Restylane® Defyne™ results in smoothed out deep laugh lines and a restored youthful appearance. Restylane® Refyne™ smoothes out and softens laugh lines while maintain a natural appearance and movement.

Schedule a Consultation

If you are interested in Restylane® Refyne™ or Defyne™, contact Laser & Mohs Dermatology of New York. Call (212) 391-8600 to schedule a consultation.

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Location Map:
501 5th Ave Suite #604 | New York, NY 10017
Hours: Monday – Friday: 7:30AM – 8PM
T. 212.391.8600 | F. 212.391.8601