dermal fillers new york city

Restylane Refyne & Defyne


Restylane® was the first dermal filler in the U.S., approved back in 2006. Since then, Restylane®, along with Juvederm®, have been the world’s most popular dermal fillers. Over the years, both product lines have expanded to specifically target areas such as the lips with Restylane® Silk or Juvederm® Volbella®.

The full Restylane® line now includes five fillers: Restylane®, Restylane® Silk, Restylane® Lyft, Restylane® Refyne™, and Restylane® Defyne™.

What is Restylane Refyne?

Restylane® Refyne was approved by the FDA in December 2016. This new addition to the Restylane® line (along with Defyne™, see below) is used to correct smile (marionette) lines and nasolabial folds. Refyne™ is specifically formulated to treat mild to moderate lines and wrinkles.

What is Restylane Defyne?

Approved by the FDA along with Refyne™, Defyne™ also specifically targets nasolabial folds and marionette lines. The difference is that Defyne™ is designed for use on moderate to severe creases and lines. Both Refyne™ and Defyne™ provide results that last up to one year.

What’s so Different About Refyne and Defyne?

There are definitely other options for addressing nasolabial folds and marionette lines, but Refyne™ and Defyne™ are different. Both of these fillers are designed with what their manufacturer, Galderma, calls XpressHAn Technology™. XpressHAn Technology™ is a cross-linking in the gel of both Restylane® Refyne™ and Defyne™ to help support the patient’s natural expressions — for real-life results that help maintain natural movement when smiling, frowning, or otherwise moving your mouth.What does this mean? If you’re reading this page, you know about dermal fillers. In some cases, injection into the nasolabial folds and other areas around the mouth can create an unnatural inability of the facial skin to move with certain facial expressions. Galderma says its technology now allows Refyne™ and Defyne™ to fill the creases, all the while letting your skin move naturally when you make expressions.

How Many Treatments Will I Need with Refyne or Defyne?

These are single session dermal fillers. One session takes just 15-20 minutes. Your results are immediate as these fillers instantly fill smile and marionette lines.

Restylane Refyne and Defyne Results

Both of these fillers provide results that last up to one year.

Schedule a Consultation

If you are interested in Restylane Refyne or Defyne, contact Laser & Mohs Dermatology of New York. Call (212) 391-8600 to schedule a consultation.

Contact Us Today

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NYC Dermatologists
130 W 42nd St #1900 | New York, NY 10036
Hours: Monday – Friday: 7:30AM – 8PM
T. 212.391.8600 | F. 212.391.8601